422 genes linked by the literature2,731 genes with papers104 clusters104 drawn (422 genes)modularity Q = 0.886
How to read this. Each dot is a cluster of genes that papers link, as named
partners or as members of the same complex. The label is the cluster's most-connected gene.
The colour is the most common hyperLOPIT compartment among the cluster's confidently
localised genes. Lines join each cluster to its strongest neighbours. Hover a dot for its
compartment, click it for its genes, and click a legend entry to highlight one compartment.
Literature-only, and incomplete by design. Links come from the partners and
complexes named in each gene's literature summary on this site, matched to gene cards by
name. This is not an interactome: no STRING, BioGRID or other network data is used. Two
clusters sit close because papers mention their genes together, not because the proteins
necessarily touch. Only genes with at least one matched link appear.
Colour = compartment
All clusters
The 104 clusters on the map, largest first. Hover a gene for its product and hyperLOPIT call.
Filters.
Non-coding RNA loci are left out, because hundreds of rDNA copies repeat the same finding.
When 8 or more genes sharing a product name all cite the same partner, those links are dropped as copies of one family member's findings.
The same rule removes such family members from a complex unless the complex name names them.
Localisation. hyperLOPIT TAGM-MAP calls for ME49 genes from Barylyuk et al. (2020)
Cell Host & Microbe 28:752–766,
doi:10.1016/j.chom.2020.09.011, via ToxoDB build 71 (released 20 August 2026 00:00), dataset "LOPIT Cellular Localization".
The study's 26 compartments are grouped into eight colours, and each gene's exact compartment shows on hover.
A gene counts as localised when its MAP probability is at least 0.99; that is this site's display threshold, not the study's own rule.
Grey marks genes the study called outliers or placed below that threshold. Light grey marks genes it did not measure, including genes without an ME49 copy.
Built 2026-09-11 from affinage_web_2026-09-11_patched.db by scripts/build_clusters.py.