IMC16

IMC16 is a constituent protein of the Toxoplasma gondii inner membrane complex (IMC), identified through epitope tagging of cyclically expressed unknown genes in tachyzoites, placing it among the cyclically expressed components of this cytoskeletal membrane system (PMID:24841368). Beyond this localization to the IMC, no further mechanistic detail about IMC16 has been characterized in the available corpus.

1. 2014 Medium

   Whether the cyclically expressed unknown gene IMC16 encoded a functional constituent of a defined subcellular structure was unknown; epitope tagging established it as a component of the Toxoplasma inner membrane complex.

   Evidence Epitope tagging and localization of representative cyclical unknown genes in T. gondii tachyzoites

   PMID:24841368

   Open questions at the time

   • The molecular function of IMC16 within the IMC is undefined
   • No binding partners or protein interactions have been mapped
   • The role of its cyclical expression in cell division is not mechanistically established