Affinage · Toxoplasma gondii

Stats

How the Toxoplasma gondii gene cards break down across strains and against other organisms, how many of them carry a literature annotation, and what the extracted findings look like.

10,904
Gene cards
orthologous groups across 4 strains
994
Annotated
9.1% of cards · ≥ 1 finding
3,748
Findings
avg 3.8 per annotated card
4,505
Source papers
distinct PMIDs in corpus
Cards by strain presence
10,904 cards · bar length = cards · annotated share in violet
Annotated Not annotated
All 4 strains 960 of 7,405 · 13%
3 strains 8 of 566 · 1%
2 strains 5 of 310 · 2%
1 strain 21 of 2,102 · 1%
1 strain · rRNA copies 0 of 521 · 0%
Single-strain cards by strain · rRNA copies excluded
StrainCardsAnnotated
ME49 516 8
GT1 467 1
RH88 686 10
VEG 433 2

A card groups the loci of one gene across strains by synteny and reciprocal best hit. Single-strain cards are not all strain-specific genes: they include paralog copies and gene models from separate strain annotations (RH88 has its own). rRNA copies are split out because the genome carries many rRNA loci and nearly all of them have literature. Annotated = at least one finding from the reading pass.

Cross-species links
Confident 1:1 orthologs in Plasmodium and human · bar length = cards
Annotated Not annotated
Plasmodium and human 78 of 453 · 17%
Plasmodium only 72 of 427 · 17%
Human only 140 of 1,123 · 12%
No confident 1:1 link 704 of 8,901 · 8%

A link is a confident one-to-one ortholog: Plasmodium from OrthoMCL groups, human by reciprocal best hit against the human proteome. Both are computed mainly from the ME49 gene: of the 2,155 cards without an ME49 locus, 0 have a Plasmodium link and 7 a human link. No confident 1:1 link means no such match was found — not that the gene is unique to Toxoplasma.

Finding confidence
Tier × preponderance · 3,748 findings
High
1,337 · 35.7%
Medium
2,071 · 55.3%
Low
340 · 9.1%

Assigned per finding by the reading pass from method tier and weight of evidence. High = direct biochemical/structural/genetic proof; Low = single-paper observational claim.

Finding year histogram
3,747 dated findings · 1971 → 2026 · 2020 onward in red
1971 1998 2026

≥ 2020: 1,412 findings (37.7% of dated). 1 finding dated after 2026 is not shown: a future year is an extraction error.